ClaimsBae™ Minis: Bacillus Coagulans
Ingredient: Bacillus Coagulans Unique IS2
Claim: Supports Gut Health
Supports Bowel Movement
Madempudi et al. (2020) evaluated the effects of B. coagulans (Unique IS2) in 100 participants diagnosed with functional constipation. In this double-blind, randomized, placebo-controlled, parallel group multicentric study, participants (18–64 years) were supplemented with either B. coagulans Unique IS2 (2×10^9 CFU) or placebo capsules once daily for 28 days. Treatment success (defined as three or more spontaneous stools per week), stool consistency, difficulty of defecation, defecation and abdominal pain was evaluated. At the end of the study, there was a statistically significant (P< 0.001) increase in number of bowel movements in the probiotic treated group as compared to placebo. 98% of participants in the probiotic group achieved normal stool consistency as compared to placebo (74%). Analyses also indicated relief from symptoms of incomplete evacuation, painful defecation and abdominal pain associated with constipation in supplemented group when compared to placebo. In conclusion, B. coagulans significantly decreased the symptoms of constipation indicating effectiveness of the strain in the negative effects of constipation, and gut health.
Study: Madempudi, R. S., Neelamraju, J., Ahire, J. J., Gupta, S. K., & Shukla, V. K. (2020). Bacillus coagulans Unique IS2 in constipation: a double-blind, placebo-controlled study. Probiotics and antimicrobial proteins, 12(2), 335-342.